新髮靈與柔沛的臨床試驗比較

收錄917名雄性禿病人之跨國多中心試驗中，排除血中睪固酮濃度<250 ng/dL者，dutasteride(新髮靈)劑量為0.02、0.1或0.5mg，治療6個月後，dutasteride(新髮靈) 0.1 mg增加髮量和頭髮粗度之效果與Finasteride(柔沛) 1 mg相當，Dutasteride(新髮靈) 0.5mg增加髮量之效果較Finasteride(柔沛)高出30%。

Dutasteride(新髮靈)用於不同嚴重程度的受試者，皆有一定程度之療效。
以Finasteride (柔沛)1 mg治療6個月後未達到顯著臨床效果的雄性禿病 人， 改以Dutasteride(新髮靈) 0.5 mg治療後，有77.4%達到程度不等之改善，於頭髮密度與粗度，平均改善了10.3%及19.8%。年輕的雄性禿病人經過24週治療後，使用dutasteride(新髮靈) 0.5 mg者單位面積髮量平均增加13根，使用Finasteride(柔沛) 1 mg者反而減少4根。

日本的研究以Dutasteride(新髮靈) 0.5 mg治療雄性禿病人，超過9成完成持續52週的治療，且頭頂和前額區域皆明顯改善，僅<1%受試者髮量減少。

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